Gonococcal Ophthalmia Neonatorum Despite Treatment with Antibacterial Eye-drops

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Gonococcal ophthalmia neonatorum despite treatment with antibacterial eye-drops.

Over a five-year period, 1964-8, 48 cases of gonococcal ophthalmia neonatorum were notified to the department of venereology in Glasgow. Thirty-seven babies were born in hospital and 11 at home. The conjunctivitis, usually recorded as a "sticky eye," developed between 1 and 13 days of birth, 36 by the fourth day.Diagnosis by culture of Neisseria gonorrhoeae was delayed in some cases up to 30 da...

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Single-dose kanamycin therapy of gonococcal ophthalmia neonatorum.

117 infants with gonococcal ophthalmia neonatorum, including 27 with infections due to penicillinase-producing Neisseria gonorrhoeae, were treated as outpatients with five different regimens of single-dose intramuscular kanamycin (75 mg or 150 mg) with saline eye washes, gentamicin eye ointment, or chloramphenicol eye drops. There were no treatment failures among 68 patients treated with 75 mg ...

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Single-dose cefotaxime intramuscularly cures gonococcal ophthalmia neonatorum.

Nine neonates with culture proved gonococcal ophthalmia neonatorum were treated with a single intramuscular injection of 100 mg/kg of cefotaxime without topical antibiotic therapy. Five of the nine strains were penicillinase-producing Neisseria gonorrhoeae. All nine cases were clinically and microbiologically cured, and no side effects were observed.

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Ophthalmia Neonatorum

Ihis work won for its author the Middleinore Piize of the British Medical Association in 1907. It contains the most complete account there is in the English language of a preventible disease winch is still responsible for a large amount of the blindness in the world. The book abounds with instructive tables taken from all available souices illustrating the prevalence, etiology, pievention and t...

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Treatment and prevention of ophthalmia neonatorum.

QUESTION In my office I occasionally see neonates with conjunctivitis. What are the current recommendations for ocular prophylaxis at birth? Do topical antibiotics alone provide adequate treatment of neonatal conjunctivitis? When is systemic therapy indicated? ANSWER All infants should receive ocular prophylaxis at birth to prevent gonococcal ophthalmia. Neonates presenting with signs of conj...

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ژورنال

عنوان ژورنال: BMJ

سال: 1971

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.1.5743.257